The corporation started as a fifteen-bed general hospital in a two-hectare lot of the once marshy and rustic atmosphere at Sta. Filomena, Dipolog City. The corporation was conceived way back on March 20, 1972 by fifteen (15) Dipolognons Medical practitioners and Monsignor Felix S. Zafra, former Archbishop of the diocese of Dipolog, by pooling their resources and expertise together. It was envisioned to provide the best medical service delivery to the people at reasonable rates. After more than two (2) years of its conceptualization and stages of planning, the hospital operation finally started its delivery services on August 1, 1974.

Following the full operation of the hospital, the members of the corporation thought of establishing a school of midwifery. It took almost two (2) years when the Bureau of Higher Education, now the Commission on Higher Education gave the approval for the school to open a Midwifery course beginning school year 1977-1978.

After several years of service to the community, the new management felt the need of training young men and women coming from the two (2) cities of Dipolog and Dapitan and the province of Zamboanga del Norte for the nursing profession. Hence, through the concerted efforts of the Chairman of the Board, Atty. Alberto P. Concha and Hospital Director, Dr. Stephen Yap, they worked for the opening of the new revised Bachelor of Science in Nursing (BSN) curriculum. Thus, the permit was granted by the Bureau of Higher Education, now Commission on Higher Education, Department of Education, Culture and Sports on April 30, 1991 to open the first year level of the College of Nursing.

The school was then known as Dipolog Medical Center College of Health and Sciences, offering only medical courses to the community.

In 1998, that name was changed to Dipolog Medical Center College Foundation, Inc. Along with the change of the name of the school comes the offer of non-medical courses like Bachelor of Science in Secondary Education, Bachelor of Science in Criminology, Bachelor of Science in Information Technology, Bachelor of Arts in Political Science, Bachelor of Science in Commerce, Bachelor in Computer Science, among others. Thus, the name Dipolog Medical Center College Foundation since the college have expanded its educational services to the community by not only offering medical courses but also non-medical courses.

The College offer of medical courses have also expanded by offering not only Nursing and Midwifery but also Physical Therapy, Medical Technology, Radiologic Technology and others.